Consultation
Keely evaluates your facial anatomy, discusses your goals, and maps precise injection points tailored to your muscle activity patterns.
Xeomin in Indianapolis, IN – Neurotoxin Wrinkle Treatment
Pure-Form Neurotoxin
Treatment Time:15-30 minutes
Results Onset:3-7 days
Duration:3-4 months
Downtime:None
Price:$11/unit
Dynamic Wrinkles Age You Faster Than You Think
A Cleaner Solution Exists
Every smile, frown, and squint etches itself a little deeper into your skin over time. Dynamic wrinkles — the lines that form from repeated facial muscle movements — become more prominent as collagen production slows with age. These wrinkles and fine lines around the forehead, between the brows, and at the corners of the eyes can make you look tired, stressed, or older than you feel, even when your skin is otherwise healthy.
Xeomin (incobotulinumtoxinA) works at the neuromuscular junction, blocking the release of acetylcholine to temporarily relax the specific muscles responsible for dynamic wrinkles. Unlike other neurotoxins, Xeomin is a naked formulation — free from complexing proteins — which means your body receives only the active therapeutic molecule. This purity may reduce the likelihood of developing neutralizing antibodies, making Xeomin an excellent option for long-term wrinkle management and a reliable alternative to other neurotoxins like Dysport.
What Is Xeomin?
The Pure-Form Neurotoxin Difference
Xeomin (incobotulinumtoxinA) is an FDA-approved injectable neurotoxin manufactured by Merz Aesthetics. First approved in the United States in 2010 for cervical dystonia and blepharospasm, Xeomin received aesthetic approval for moderate to severe glabellar lines in 2011. It works by blocking the release of acetylcholine at the neuromuscular junction, temporarily preventing targeted muscle contractions that cause dynamic wrinkles.
What sets Xeomin apart from other botulinum toxin type A products is its unique purification process. Through a proprietary manufacturing technique called XTRACT Technology, complexing proteins are removed from the active neurotoxin molecule. This results in a "naked" 150-kDa neurotoxin — the lowest molecular weight of any commercially available botulinum toxin. Clinical research suggests this purity may reduce the formation of neutralizing antibodies that can diminish treatment effectiveness over time, making Xeomin particularly well-suited for patients who require ongoing neurotoxin treatments.
Treatment Timeline
Treatment Time
15-30 minutes
First Signs
3-5 days post-injection
Full Effect
7-14 days (peak results)
Duration
3-4 months per session
Recovery
No downtime — resume activities immediately
Benefits of Xeomin
Pure-Form Advantages
- 01
Pure Formulation
Free from complexing proteins, reducing the risk of antibody resistance over time
- 02
No Downtime
Return to your daily routine immediately after treatment
- 03
Natural Results
Softens wrinkles while preserving natural facial expression and movement
- 04
Quick Treatment
Most sessions completed in 15 to 30 minutes during a lunch break
- 05
Proven Efficacy
Phase III trials showed up to 93% responder rates for glabellar lines
Xeomin vs Botox vs Dysport vs Daxxify
Compare Neurotoxins
| Treatment | Formulation | Onset | Duration | Unit Price | Best For | FDA Approved |
|---|---|---|---|---|---|---|
| Xeomin | Pure (no complexing proteins) | 3-5 days | 3-4 months | $11/unit | Long-term use, antibody concerns | Yes (2011) |
| Botox | OnabotulinumtoxinA with proteins | 3-5 days | 3-4 months | $12-15/unit | Established track record, widespread use | Yes (2002) |
| Dysport | AbobotulinumtoxinA with proteins | 2-3 days | 3-4 months | $4-5/unit | Faster onset, larger treatment areas | Yes (2009) |
| Daxxify | DaxibotulinumtoxinA (peptide stabilized) | 3-5 days | 6-9 months | $12-16/unit | Longer-lasting results between visits | Yes (2022) |
Xeomin Frown Lines
Xeomin Frown Lines
Real Results
Most patients notice initial smoothing within 3 to 5 days of their Xeomin treatment, with full results becoming visible at 7 to 14 days. Results typically last 3 to 4 months, and patients who maintain a consistent treatment schedule often find their results improve over time as the muscles gradually weaken with repeated treatments.
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Who Is a Good Candidate for Xeomin?
Candidacy and Considerations
Xeomin is well-suited for adults who want to soften dynamic wrinkles or address medical concerns like TMJ and jaw pain or hyperhidrosis (excessive sweating). It is an especially strong choice for patients who have used other neurotoxins previously and want a pure-form alternative, or for those beginning neurotoxin treatment for the first time.
Ideal Candidates for Xeomin
- Adults aged 18 and older with moderate to severe dynamic wrinkles
- Patients seeking a pure-form neurotoxin free from complexing proteins
- Those who have developed resistance or reduced response to other botulinum toxin products
- Individuals with TMJ-related jaw pain or teeth grinding
- Patients with primary axillary hyperhidrosis unresponsive to topical treatments
- Anyone in good overall health with realistic expectations for natural-looking improvement
Who Should Wait or Avoid Xeomin
- Known hypersensitivity to botulinum toxin type A or any formulation excipients
- Active skin infection at the planned injection site
- Pregnancy or breastfeeding
- Diagnosed neuromuscular disorders such as myasthenia gravis or Lambert-Eaton syndrome
- Current use of aminoglycoside antibiotics or other agents that interfere with neuromuscular transmission
All patients receive a thorough consultation with Keely before treatment to ensure Xeomin is appropriate for their individual anatomy and goals. Contraindicated conditions are screened during intake.
What Happens During Your Xeomin Visit
Preparation
Keely cleanses the treatment area and may apply a topical numbing cream or cold compress to maximize your comfort during injection.
Injection
Using ultra-fine 30-gauge needles, Keely delivers carefully measured Xeomin units into each targeted muscle with her artistry-driven technique.
Review
Keely reviews aftercare instructions — including avoiding rubbing the area and staying upright for 4 hours — and schedules your follow-up.
Side Effects and Safety
What to Know
Xeomin has a well-established safety profile supported by extensive clinical trials. The most common side effects are mild and temporary, typically resolving within a few days.
Common side effects include mild redness, swelling, or bruising at injection sites, headache (reported in approximately 5% of patients in clinical trials), and temporary eyelid heaviness or drooping in rare cases when treating the upper face.
Less common effects may include mild asymmetry during the onset period, dry eyes or excessive tearing, and localized muscle weakness adjacent to the injection site.
Serious adverse events are extremely rare when Xeomin is administered by a qualified provider. The FDA boxed warning notes the theoretical risk of toxin spread beyond the injection site, though this has not been reported at cosmetic doses. Keely follows strict dosing protocols and anatomical guidelines to minimize risk.
If you experience difficulty swallowing, breathing, or speaking after treatment, seek medical attention immediately. Contact Mint Aesthetics & Skin at (317) 748-3169 with any post-treatment concerns.
Xeomin Cost in Indianapolis
Transparent Per-Unit Pricing
Xeomin at Mint Aesthetics & Skin is priced at $11 per unit, making it one of the most competitively priced neurotoxin options in the Indianapolis area. Your total cost depends on the number of units needed to achieve your desired results.
Forehead Lines
10-30 units
$110-$330
Frown Lines (Glabellar)
20 units
$220
Crow's Feet
12-24 units
$132-$264
Lip Flip
4-8 units
$44-$88
TMJ / Masseter
40-60 units per side
$440-$660
Hyperhidrosis (Underarms)
50-100 units per side
$550-$1,100
During your consultation, Keely will assess your facial anatomy and muscle strength to recommend the precise number of units for your goals. Xeomin is also eligible for the Merz Aesthetics Xperience+ loyalty program, which offers rewards toward future treatments. Contact us at (317) 748-3169 to schedule your consultation and receive a personalized quote.
Why Choose Mint Aesthetics & Skin
Indianapolis Injection Experts
Artistry-Driven Technique
Design training informs precise injection placement for harmonious results
Certified Expertise
PA credentials and specialized aesthetic injector training ensure clinical safety
Personalized Dosing
Custom unit counts based on your unique muscle strength and treatment goals
Warm, Empowering Care
A welcoming Broad Ripple Village experience focused on your confidence
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Xeomin Frequently Asked Questions
Answers from Keely Phelps, PA
01 What is the difference between Xeomin and Botox?
Both Xeomin and Botox are botulinum toxin type A products that temporarily relax facial muscles. The key difference is formulation: Xeomin is a pure-form neurotoxin free from complexing proteins, while Botox contains accessory proteins. This purity may reduce the risk of developing antibody resistance with long-term use. Efficacy, onset, and duration are clinically equivalent at standard cosmetic doses.
02 How long does Xeomin last?
Xeomin results typically last 3 to 4 months, similar to Botox and Dysport. Some patients find their results extend longer with consistent treatment over time, as the targeted muscles gradually weaken. Keely will recommend a personalized maintenance schedule during your consultation.
03 Does Xeomin hurt?
Most patients describe Xeomin injections as a brief, mild pinch. Keely uses ultra-fine needles and can apply topical numbing cream or a cold compress beforehand to maximize comfort. The entire treatment typically takes 15 to 30 minutes, and any discomfort resolves within minutes.
04 How much does Xeomin cost?
Xeomin at Mint Aesthetics & Skin is $11 per unit. Total cost varies by treatment area — for example, frown lines typically require about 20 units ($220), while forehead lines may need 10 to 30 units ($110-$330). Keely provides a personalized unit recommendation during your consultation.
05 Is Xeomin better than Botox?
Neither is universally better — the best neurotoxin depends on your individual needs. Xeomin's advantage is its pure formulation, which may benefit patients concerned about long-term antibody development. Botox has a longer track record and wider familiarity. Both produce equivalent clinical results for cosmetic wrinkle reduction.
06 What is a lip flip?
A lip flip is a subtle enhancement that uses a small number of Xeomin units (typically 4 to 8) injected into the orbicularis oris muscle along the upper lip border. This relaxes the muscle just enough to allow the upper lip to gently roll outward, creating the appearance of fuller lips without filler. Results last approximately 6 to 8 weeks.
07 Can Xeomin treat TMJ?
Yes. Xeomin can be injected into the masseter muscles to reduce jaw clenching, teeth grinding, and associated TMJ pain. By relaxing these overactive muscles, Xeomin alleviates tension headaches and jaw soreness while also creating a slimmer facial profile. Treatment typically requires 40 to 60 units per side.
Location2015 Broad Ripple Avenue
Indianapolis, IN, 46220
Indianapolis, IN, 46220
Phone(317) 748-3169
Schedule Your Xeomin Consultation
References
- PubMed (PMID: 25111351) - Pooled analysis of two Phase III trials demonstrated up to 93.1% responder rate for incobotulinumtoxinA in glabellar frown lines with sustained efficacy at 120 days.
- PubMed (PMID: 26509943) - Randomized double-blind trial confirmed therapeutic equivalence of incobotulinumtoxinA and onabotulinumtoxinA at 20 units for glabellar frown lines through 4 months.
- PubMed (PMID: 22035051) - Five-year clinical experience with incobotulinumtoxinA demonstrated consistent efficacy as the first botulinum toxin free of complexing proteins with favorable long-term safety.
- PubMed (PMID: 31960136) - Cross-sectional study confirmed effective long-term incobotulinumtoxinA treatment without neutralizing antibody induction, supporting its pure-form advantage.
- PubMed (PMID: 34636520) - Dose-ranging study showed prolonged duration of effect with incobotulinumtoxinA, with median duration reaching 120 days at 20 units and up to 270 days at higher doses.